Thrombophlebitis (throm-boe-fluh-BY-tis) is an inflammatory process that causes a blood clot to form and block one or more veins, usually in your legs. The affected vein might be near the surface of your skin (superficial thrombophlebitis) or deep within a muscle (deep vein thrombosis, or DVT). Causes include trauma, surgery or prolonged inactivity.
DVT increases your risk of serious health problems. It's usually treated with blood-thinning medications. Superficial thrombophlebitis is sometimes treated with blood-thinning medications, too.
Superficial thrombophlebitis signs and symptoms include:
- Warmth, tenderness and pain in the affected area
- Redness and swelling
Deep vein thrombosis signs and symptoms include:
When a vein close to the surface of your skin is affected, you might see a red, hard cord just under the surface of your skin that's tender to the touch. When a deep vein in the leg is affected, your leg may become swollen, tender and painful.
The cause of thrombophlebitis is a blood clot, which can form in your blood as a result of:
- An injury to a vein
- An inherited blood-clotting disorder
- Being immobile for long periods, such as during an injury or a hospital stay
Your risk of thrombophlebitis increases if you:
- Are inactive for a prolonged period, either because you're confined to bed or are traveling in a car or plane for a long period
- Have varicose veins, which are a common cause of superficial thrombophlebitis
- Have a pacemaker or have a thin, flexible tube (catheter) in a central vein, for treatment of a medical condition, which may irritate the blood vessel wall and decrease blood flow
- Are pregnant or have just given birth
- Use birth control pills or hormone replacement therapy, which can make your blood more likely to clot
- Have a family history of a blood-clotting disorder or a tendency to form blood clots
- Have had previous episodes of thrombophlebitis
- Have had a stroke
- Are older than 60
- Are overweight or obese
- Have cancer
- Smoke
Complications from superficial thrombophlebitis are rare. However, if you develop DVT, the risk of serious complications increases. Complications might include:
- Pulmonary embolism. If part of a deep vein clot becomes dislodged, it can travel to your lungs, where it can block an artery (embolism) and become potentially life-threatening.
- Post-phlebetic syndrome. This condition, also known as post-thrombotic syndrome, can develop months or even years after you've had DVT. Post-phlebetic syndrome can cause lasting and possibly disabling pain, swelling and a feeling of heaviness in the affected leg.