Botulism is a rare but serious condition caused by toxins from bacteria called Clostridium botulinum.
Three common forms of botulism are:
- Foodborne botulism. The harmful bacteria thrive and produce the toxin in environments with little oxygen, such as in home-canned food.
- Wound botulism. If these bacteria get into a cut, they can cause a dangerous infection that produces the toxin.
- Infant botulism. This most common form of botulism begins after Clostridium botulinum bacterial spores grow in a baby's intestinal tract. It typically occurs in babies between the ages of 2 months and 8 months.
All types of botulism can be fatal and are considered medical emergencies.
Foodborne botulism
Signs and symptoms of foodborne botulism typically begin between 12 and 36 hours after the toxin gets into your body. But, depending on how much toxin was consumed, the start of symptoms may range from a few hours to a few days. Signs and symptoms of foodborne botulism include:
- Difficulty swallowing or speaking
- Dry mouth
- Facial weakness on both sides of the face
- Blurred or double vision
- Drooping eyelids
- Trouble breathing
- Nausea, vomiting and abdominal cramps
- Paralysis
Wound botulism
Signs and symptoms of wound botulism appear about 10 days after the toxin has entered the body. Wound botulism signs and symptoms include:
- Difficulty swallowing or speaking
- Facial weakness on both sides of the face
- Blurred or double vision
- Drooping eyelids
- Trouble breathing
- Paralysis
The wound may or may not appear red and swollen.
Infant botulism
If infant botulism is related to food, such as honey, problems generally begin within 18 to 36 hours after the toxin enters the baby's body. Signs and symptoms include:
- Constipation, which is often the first sign
- Floppy movements due to muscle weakness and trouble controlling the head
- Weak cry
- Irritability
- Drooling
- Drooping eyelids
- Tiredness
- Difficulty sucking or feeding
- Paralysis
Certain signs and symptoms usually don't occur with botulism. For example, botulism doesn't generally increase blood pressure or heart rate, or cause fever or confusion. Sometimes, however, wound botulism may cause fever.
Foodborne botulism
The source of foodborne botulism is often home-canned foods that are low in acid, such as fruits, vegetables and fish. However, the disease has also occurred from spicy peppers (chiles), foil-wrapped baked potatoes and oil infused with garlic.
When you eat food containing the toxin, it disrupts nerve function, causing paralysis.
Wound botulism
When C. botulinum bacteria get into a wound — possibly caused by an injury you might not notice — they can multiply and produce toxin. Wound botulism has increased in recent decades in people who inject heroin, which can contain spores of the bacteria. In fact, this type of botulism is more common in people who inject black tar heroin.
Infant botulism
Babies get infant botulism after consuming spores of the bacteria, which then grow and multiply in their intestinal tracts and make toxins. The source of infant botulism may be honey, but it's more likely to be exposure to soil contaminated with the bacteria.
Are there benefits to botulinum toxin?
You might wonder how something so toxic could ever be beneficial, but scientists have found that the paralyzing effect of botulinum toxin makes it useful in certain circumstances.
Botulinum toxin has been used to reduce facial wrinkles by preventing contraction of muscles beneath the skin and for medical conditions, such as eyelid spasms and severe headaches. However, there have been rare occurrences of serious side effects, such as muscle paralysis extending beyond the treated area, with the use of botulinum toxin for medical reasons. Be sure to use a licensed doctor for any cosmetic or medical procedures using onabotulinumtoxinA (Botox).
Because it affects muscle control throughout your body, botulinum toxin can cause many complications. The most immediate danger is that you won't be able to breathe, which is the most common cause of death in botulism. Other complications, which may require rehabilitation, may include:
- Difficulty speaking
- Trouble swallowing
- Long-lasting weakness
- Shortness of breath